Transcriptome profiling of antiviral immune and dietary fatty acid dependent responses of Atlantic salmon macrophage-like cells
作者: Khalil EslamlooXi XueJennifer R. HallNicole C. SmithAlbert Caballero-SolaresChristopher C. ParrishRichard G. TaylorMatthew L. Rise
作者单位: 1Memorial University of Newfoundland
2Cargill Innovation Center
刊名: BMC Genomics, 2017, Vol.18 (1)
来源数据库: Springer Journal
DOI: 10.1186/s12864-017-4099-2
关键词: MicroarrayNutrigenomicsTeleost fishOmega-3/omega-6 fatty acidsPoly(I:C)Pathogen recognitionFABP4
英文摘要: Due to the limited availability and high cost of fish oil in the face of increasing aquaculture production, there is a need to reduce usage of fish oil in aquafeeds without compromising farm fish health. Therefore, the present study was conducted to determine if different levels of vegetable and fish oils can alter antiviral responses of salmon macrophage-like cells (MLCs). Atlantic salmon ( Salmo salar ) were fed diets containing 7.4% (FO7) or 5.1% (FO5) fish oil. These diets were designed to be relatively low in EPA + DHA (i.e. FO7: 1.41% and FO5: 1%), but near the requirement level, and resulting in comparable growth. Vegetable oil (i.e. rapeseed oil) was used to balance fish oil in experimental diets. After a 16-week feeding trial, MLCs isolated from fish in these dietary groups were...
原始语种摘要: Due to the limited availability and high cost of fish oil in the face of increasing aquaculture production, there is a need to reduce usage of fish oil in aquafeeds without compromising farm fish health. Therefore, the present study was conducted to determine if different levels of vegetable and fish oils can alter antiviral responses of salmon macrophage-like cells (MLCs). Atlantic salmon ( Salmo salar ) were fed diets containing 7.4% (FO7) or 5.1% (FO5) fish oil. These diets were designed to be relatively low in EPA + DHA (i.e. FO7: 1.41% and FO5: 1%), but near the requirement level, and resulting in comparable growth. Vegetable oil (i.e. rapeseed oil) was used to balance fish oil in experimental diets. After a 16-week feeding trial, MLCs isolated from fish in these dietary groups were...
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影响因子:4.397 (2012)

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关键词翻译
关键词翻译
  • salmon 鲑鱼
  • Atlantic 在西洋的
  • aquaculture 水培
  • fatty 脂肪的
  • dietary 饮食的
  • salar 干盐湖
  • feeding 供给
  • profiling 仿形切削
  • macrophage 巨噬细胞
  • rapeseed 油菜子