XIAP over-expression is an independent poor prognostic marker in Middle Eastern breast cancer and can be targeted to induce efficient apoptosis
作者: Azhar R. HussainAbdul Khalid SirajMaqbool AhmedRong BuPoyil PratheeshkumarAlanood M. AlrashedZeeshan QadriDahish AjarimFouad Al-DayelShaham BegKhawla S. Al-Kuraya
作者单位: 1King Faisal Specialist Hospital and Research Cancer
2AlFaisal University
3King Faisal Specialist Hospital and Research Center
刊名: BMC Cancer, 2017, Vol.17 (1)
来源数据库: Springer Journal
DOI: 10.1186/s12885-017-3627-4
关键词: Breast cancerXIAPEmbelinP-AKTApoptosis
英文摘要: Breast cancer is the most common cancer in females and is ranked second in cancer-related deaths all over the world in women. Despite improvement in diagnosis, the survival rate of this disease has still not improved. X-linked Inhibitor of Apoptosis (XIAP) has been shown to be over-expressed in various cancers leading to poor overall survival. However, the role of XIAP in breast cancer from Middle Eastern region has not been fully explored.
原始语种摘要: Breast cancer is the most common cancer in females and is ranked second in cancer-related deaths all over the world in women. Despite improvement in diagnosis, the survival rate of this disease has still not improved. X-linked Inhibitor of Apoptosis (XIAP) has been shown to be over-expressed in various cancers leading to poor overall survival. However, the role of XIAP in breast cancer from Middle Eastern region has not been fully explored.
全文获取路径: Springer  (合作)
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影响因子:3.333 (2012)

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关键词翻译
关键词翻译
  • expression 表示
  • targeted 对准目标的
  • marker 标试器
  • Middle 中级牌黄麻
  • breast 胸部
  • cancer 癌症
  • region 地域
  • fully 充分
  • over 在上方
  • expressed 榨出的