miR-19b-3p promotes colon cancer proliferation and oxaliplatin-based chemoresistance by targeting SMAD4: validation by bioinformatics and experimental analyses
作者: Tao JiangLing YeZhongbo HanYuan LiuYinxue YangZhihai PengJunwei Fan
作者单位: 1General Hospital of Ningxia Medical University
2Shanghai Jiao Tong University School of Medicine
3Central Hospital of Zi Bo
刊名: Journal of Experimental & Clinical Cancer Research, 2017, Vol.36 (1)
来源数据库: Springer Journal
DOI: 10.1186/s13046-017-0602-5
关键词: MiR-19b-3pSMAD4ProliferationOxaliplatinChemoresistance
英文摘要: As a disease with extremely complex molecular mechanisms, many deregulated miRNAs have been identified in colon cancer. Few studies have been performed by using Ingenuity Pathways Analysis (IPA) to predict miRNAs specifically expressed in colon cancer.
原始语种摘要: As a disease with extremely complex molecular mechanisms, many deregulated miRNAs have been identified in colon cancer. Few studies have been performed by using Ingenuity Pathways Analysis (IPA) to predict miRNAs specifically expressed in colon cancer.
全文获取路径: Springer  (合作)
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关键词翻译
关键词翻译
  • targeting 导向目标
  • colon 结肠
  • cancer 癌症
  • proliferation 增生
  • bioinformatics 生物信息学
  • expressed 榨出的
  • experimental 实验的
  • validation 证实
  • specifically 明确地
  • complex 超群