Giardia -specific cellular immune responses in post-giardiasis chronic fatigue syndrome
作者: Kurt HanevikEinar KristoffersenKristine MørchKristin Paulsen RyeSteinar SørnesStaffan SvärdØystein BruserudNina Langeland
作者单位: 1Lab-building 8.floor, University of Bergen
2Haukeland University Hospital
3Uppsala University
刊名: BMC Immunology, 2017, Vol.18 (1)
来源数据库: Springer Journal
DOI: 10.1186/s12865-017-0190-3
关键词: GiardiaT cellChronic fatigue syndromeAntigen-specificImmune responseSCD40L
英文摘要: The role of pathogen specific cellular immune responses against the eliciting pathogen in development of post-infectious chronic fatigue syndrome (PI-CFS) is not known and such studies are difficult to perform. The aim of this study was to evaluate specific anti- Giardia cellular immunity in cases that developed CFS after Giardia infection compared to cases that recovered well. Patients reporting chronic fatigue in a questionnaire study three years after a Giardia outbreak were clinically evaluated five years after the outbreak and grouped according to Fukuda criteria for CFS and idiopathic chronic fatigue. Giardia specific immune responses were evaluated in 39 of these patients by proliferation assay, T cell activation and cytokine release analysis. 20 Giardia exposed non-fatigued...
原始语种摘要: The role of pathogen specific cellular immune responses against the eliciting pathogen in development of post-infectious chronic fatigue syndrome (PI-CFS) is not known and such studies are difficult to perform. The aim of this study was to evaluate specific anti- Giardia cellular immunity in cases that developed CFS after Giardia infection compared to cases that recovered well. Patients reporting chronic fatigue in a questionnaire study three years after a Giardia outbreak were clinically evaluated five years after the outbreak and grouped according to Fukuda criteria for CFS and idiopathic chronic fatigue. Giardia specific immune responses were evaluated in 39 of these patients by proliferation assay, T cell activation and cytokine release analysis. 20 Giardia exposed non-fatigued...
全文获取路径: Springer  (合作)
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来源刊物:
影响因子:2.61 (2012)

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关键词翻译
关键词翻译
  • giardiasis 贾第虫病
  • fatigue 疲劳
  • chronic 延续很长的
  • immune 免疫的
  • specific 
  • cellular 细胞状的
  • unexposed 未受辐射的
  • syndrome 症候群
  • cytokine 细胞因子
  • controls 控制机构