The inhibitory effects of compound Muniziqi granule against B16 cells and harmine induced autophagy and apoptosis by inhibiting Akt/mTOR pathway
作者: Nan ZouYue WeiFenghua LiYang YangXuemei ChengChanghong Wang
作者单位: 1Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, The MOE Key Laboratory for Standardization of Chinese Medicines and The SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicine
2Shanghai University of Traditional Chinese Medicine
3Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, The MOE Key Laboratory for Standardizati
刊名: BMC Complementary and Alternative Medicine, 2017, Vol.17 (1)
来源数据库: Springer Journal
DOI: 10.1186/s12906-017-2017-4
关键词: Compound Muniziqi granuleMelanomaHarmineAutophagyApoptosisAkt/mTOR pathway
英文摘要: Compound Muniziqi granule (MNZQ) is a multi-component herbal preparation and a popular traditional Uighur medicine used in China for treating endocrine disorder-induced acne, chloasma, dysmenorrhea, menopausal syndrome, and melanoma. Harmine presented in MNZQ has been confirmed potential anticancer effect on the B16 cells among others. The purpose of this study is to explore the inhibitory effects of MNZQ against B16 cells and mechanism of autophagy and apoptosis induced by harmine in B16 cells.
原始语种摘要: Compound Muniziqi granule (MNZQ) is a multi-component herbal preparation and a popular traditional Uighur medicine used in China for treating endocrine disorder-induced acne, chloasma, dysmenorrhea, menopausal syndrome, and melanoma. Harmine presented in MNZQ has been confirmed potential anticancer effect on the B16 cells among others. The purpose of this study is to explore the inhibitory effects of MNZQ against B16 cells and mechanism of autophagy and apoptosis induced by harmine in B16 cells.
全文获取路径: Springer  (合作)
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来源刊物:
影响因子:2.082 (2012)

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关键词翻译
关键词翻译
  • granule 砂砾
  • induced 感应的
  • harmine 哈尔碱
  • against 反对
  • cells 麻风细胞
  • inhibitory 禁止的
  • inhibiting 抑制
  • pathway 轨道
  • autophagy 自体消瘦
  • chloasma 褐黄斑