Transcriptional analysis of abdominal fat in chickens divergently selected on bodyweight at two ages reveals novel mechanisms controlling adiposity: validating visceral adipose tissue as a dynamic endocrine and metabolic organ
作者: C. W. ResnykW. CarréX. WangT. E. PorterJ. SimonE. Le Bihan-DuvalM. J. DuclosS. E. AggreyL. A. Cogburn
作者单位: 1University of Delaware
2CHU Pontchaillou
3Tennessee State University
4University of Maryland
5Institut National de la Recherche Agronomique (INRA)
6University of Georgia
刊名: BMC Genomics, 2017, Vol.18 (1)
来源数据库: Springer Journal
DOI: 10.1186/s12864-017-4035-5
关键词: Divergent genetic selectionGene expressionMicroarray analysisRNA-Seq analysisAdiposityLipogenesisTranscriptional regulationHemostasis genesEndocrine signaling
英文摘要: Decades of intensive genetic selection in the domestic chicken ( Gallus gallus domesticus ) have enabled the remarkable rapid growth of today’s broiler (meat-type) chickens. However, this enhanced growth rate was accompanied by several unfavorable traits (i.e., increased visceral fatness, leg weakness, and disorders of metabolism and reproduction). The present descriptive analysis of the abdominal fat transcriptome aimed to identify functional genes and biological pathways that likely contribute to an extreme difference in visceral fatness of divergently selected broiler chickens.
原始语种摘要: Decades of intensive genetic selection in the domestic chicken ( Gallus gallus domesticus ) have enabled the remarkable rapid growth of today’s broiler (meat-type) chickens. However, this enhanced growth rate was accompanied by several unfavorable traits (i.e., increased visceral fatness, leg weakness, and disorders of metabolism and reproduction). The present descriptive analysis of the abdominal fat transcriptome aimed to identify functional genes and biological pathways that likely contribute to an extreme difference in visceral fatness of divergently selected broiler chickens.
全文获取路径: Springer  (合作)
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影响因子:4.397 (2012)

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关键词翻译
关键词翻译
  • visceral 内脏的
  • adiposity 肥胖
  • adipose 脂肪的
  • abdominal 腹部的
  • analysis 分析
  • metabolic 新陈代谢的
  • endocrine 内分泌的
  • selected 被选
  • unfavorable 不利
  • novel 长篇小说