Performances of Different Fragment Sizes for Reduced Representation Bisulfite Sequencing in Pigs
作者: Xiao-Long YuanZhe ZhangRong-Yang PanNing GaoXi DengBin LiHao ZhangPer Torp SangildJia-Qi Li
作者单位: 1South China Agricultural University
2University of Copenhagen
3Georg-August University
刊名: Biological Procedures Online, 2017, Vol.19 (1)
来源数据库: Springer Journal
DOI: 10.1186/s12575-017-0054-5
关键词: DNA methylationRRBSDifferent fragment sizesPigs
英文摘要: Reduced representation bisulfite sequencing (RRBS) has been widely used to profile genome-scale DNA methylation in mammalian genomes. However, the applications and technical performances of RRBS with different fragment sizes have not been systematically reported in pigs, which serve as one of the important biomedical models for humans. The aims of this study were to evaluate capacities of RRBS libraries with different fragment sizes to characterize the porcine genome.
原始语种摘要: Reduced representation bisulfite sequencing (RRBS) has been widely used to profile genome-scale DNA methylation in mammalian genomes. However, the applications and technical performances of RRBS with different fragment sizes have not been systematically reported in pigs, which serve as one of the important biomedical models for humans. The aims of this study were to evaluate capacities of RRBS libraries with different fragment sizes to characterize the porcine genome.
全文获取路径: Springer  (合作)
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影响因子:0.95 (2012)

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关键词翻译
关键词翻译
  • fragment 碎屑
  • sequencing 排序
  • evaluate 求...的值
  • genome 基因组
  • mammalian 哺乳动物
  • representation 表现
  • bisulfite 亚硫酸氢盐
  • widely 广泛地
  • important 重要的
  • systematically 系统地