Phylogeny analysis from gene-order data with massive duplications
作者: Lingxi ZhouYu LinBing FengJieyi ZhaoJijun Tang
作者单位: 1University of South Carolina
2Australian National University
3University of Texas School of Biomedical Informatics at Houston
4Tianjin University
刊名: BMC Genomics, 2017, Vol.18 (7)
来源数据库: Springer Journal
DOI: 10.1186/s12864-017-4129-0
关键词: Phylogeny reconstructionMaximum likelihoodVariable length binary encodingWhole genome duplication
英文摘要: Gene order changes, under rearrangements, insertions, deletions and duplications, have been used as a new type of data source for phylogenetic reconstruction. Because these changes are rare compared to sequence mutations, they allow the inference of phylogeny further back in evolutionary time. There exist many computational methods for the reconstruction of gene-order phylogenies, including widely used maximum parsimonious methods and maximum likelihood methods. However, both methods face challenges in handling large genomes with many duplicated genes, especially in the presence of whole genome duplication.
原始语种摘要: Gene order changes, under rearrangements, insertions, deletions and duplications, have been used as a new type of data source for phylogenetic reconstruction. Because these changes are rare compared to sequence mutations, they allow the inference of phylogeny further back in evolutionary time. There exist many computational methods for the reconstruction of gene-order phylogenies, including widely used maximum parsimonious methods and maximum likelihood methods. However, both methods face challenges in handling large genomes with many duplicated genes, especially in the presence of whole genome duplication.
全文获取路径: Springer  (合作)
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影响因子:4.397 (2012)

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关键词翻译
关键词翻译
  • 计算的 距离
  • phylogeny 种系发生
  • reconstruction 复原
  • duplication 重复
  • phylogenetic 门的
  • likelihood 似然
  • maximum 最大值
  • genome 基因组
  • evolutionary 进化
  • length 距离
  • computational 距离