Evaluation of the association between urinary cadmium levels below threshold limits and the risk of diabetes mellitus: a dose-response meta-analysis
作者: Fei-Fei GuoZhi-Yong HuBing-Yan LiLi-Qiang QinChunling FuHuifang YuZeng-Li Zhang
作者单位: 1Jiaxing Center for Disease Control and Prevention
2Department of Nutrition and Food Hygiene, School of Public Health, Soochow University
3Department of Labor Hygiene and Environmental Health, School of Public Health, Soochow University
刊名: Environmental Science and Pollution Research, 2019, Vol.26 (19), pp.19272-19281
来源数据库: Springer Journal
DOI: 10.1007/s11356-019-04943-3
关键词: CadmiumDiabetes mellitusPancreatic β cellsMeta-analysisDose-response analysis
英文摘要: Abstract(#br)As cadmium levels are increasing in the environment, the adverse effects of cadmium exposure specifically associated with chronic diseases are receiving increasing attention. Several population–based studies have been conducted on the association between cadmium and diabetes mellitus (DM) but have reported controversial results. Here, we aimed to evaluate the association between cadmium exposure and DM. In this meta-analysis, a random effects model was used because there was evidence of heterogeneity among studies. A dose-response relationship was assessed through a restricted cubic spline model with three knots. The results showed a positive association between cadmium levels in the body and DM (OR = 1.27; 95% CI, 1.07–1.52). The cadmium levels in the body were defined on...
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影响因子:2.618 (2012)

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