An improved genome assembly uncovers prolific tandem repeats in Atlantic cod
作者: Ole K. TørresenBastiaan StarSissel JentoftWilliam B. ReinarHarald GroveJason R. MillerBrian P. WalenzJames KnightJenny M. EkholmPaul PelusoRolf B. EdvardsenAve Tooming-KlunderudMorten SkageSigbjørn LienKjetill S. JakobsenAlexander J. Nederbragt
作者单位: 1University of Oslo
2University of Agder
3Norwegian University of Life Sciences
4J. Craig Venter Institute
5Genome Informatics Section, Computational and Statistical Genomics Branch, National Human Genome Research Institute, National Institutes of Health
6Yale School of Medicine, Yale University
7Pacific Biosciences
8Institute of Marine Research
刊名: BMC Genomics, 2017, Vol.18 (1)
来源数据库: Springer Journal
DOI: 10.1186/s12864-016-3448-x
关键词: Assembly algorithmsAssembly consolidationDinucleotide repeatsGadus morhuaHeterozygosityIndel polymorphismLong-read sequencing technologyMicrosatellitesPacBioRepetitive DNA
英文摘要: The first Atlantic cod ( Gadus morhua ) genome assembly published in 2011 was one of the early genome assemblies exclusively based on high-throughput 454 pyrosequencing. Since then, rapid advances in sequencing technologies have led to a multitude of assemblies generated for complex genomes, although many of these are of a fragmented nature with a significant fraction of bases in gaps. The development of long-read sequencing and improved software now enable the generation of more contiguous genome assemblies.
原始语种摘要: The first Atlantic cod ( Gadus morhua ) genome assembly published in 2011 was one of the early genome assemblies exclusively based on high-throughput 454 pyrosequencing. Since then, rapid advances in sequencing technologies have led to a multitude of assemblies generated for complex genomes, although many of these are of a fragmented nature with a significant fraction of bases in gaps. The development of long-read sequencing and improved software now enable the generation of more contiguous genome assemblies.
全文获取路径: Springer  (合作)
分享到:
来源刊物:
影响因子:4.397 (2012)

×
关键词翻译
关键词翻译
  • genome 基因组
  • sequencing 排序
  • assembly 组装
  • exclusively 专用于
  • improved 改进
  • Atlantic 在西洋的
  • although 虽然
  • prolific 多产的
  • polymorphism 多晶形
  • contiguous 连续