The utility of apoptosis inhibitor of macrophages as a possible diagnostic marker in patients with Crohn’s disease
作者: Yohei OnoShuji KanmuraYuko MorinagaKohei OdaKatsuto KawabataShiho ArimaFumisato SasakiYuichirou NasuShiroh TanoueShinichi HashimotoHiroki TaguchiHirofumi UtoHirohito TsubouchiAkio Ido
作者单位: 1Kagoshima University Graduate School of Medical and Dental Sciences
2Miyazaki Medical Center Hospital
3Kagoshima City Hospital
刊名: BMC Gastroenterology, 2017, Vol.17 (1)
来源数据库: Springer Journal
DOI: 10.1186/s12876-017-0591-z
关键词: Inflammatory bowel diseasesCrohn’s diseaseMacrophagesApoptosis inhibitor of macrophages
英文摘要: Apoptosis inhibitor of macrophages (AIM) was initially identified as an apoptosis inhibitor that supports the survival of macrophages against various apoptosis-inducing stimuli, and AIM produced by macrophages may contribute to the pathogenesis of inflammatory bowel diseases (IBDs). However, there have been no reports on the kinetics of AIM in IBD and the impact of AIM on the pathogenesis of IBD. In this study, we aimed to investigate the diagnostic utility of levels of AIM and their correlation with the activity of Crohn’s disease (CD) and IBD.
原始语种摘要: Apoptosis inhibitor of macrophages (AIM) was initially identified as an apoptosis inhibitor that supports the survival of macrophages against various apoptosis-inducing stimuli, and AIM produced by macrophages may contribute to the pathogenesis of inflammatory bowel diseases (IBDs). However, there have been no reports on the kinetics of AIM in IBD and the impact of AIM on the pathogenesis of IBD. In this study, we aimed to investigate the diagnostic utility of levels of AIM and their correlation with the activity of Crohn’s disease (CD) and IBD.
全文获取路径: Springer  (合作)
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来源刊物:
影响因子:2.11 (2012)

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关键词翻译
关键词翻译
  • macrophages 巨噬细胞
  • apoptosis 细胞死
  • inhibitor 抑制剂
  • diagnostic 诊断的
  • pathogenesis 发病机理
  • marker 标试器
  • utility 有用
  • inflammatory 激怒的
  • survival 生存
  • AIM Access Isolation Mechanism