Dietary supplementation of curcumin augments heat stress tolerance through upregulation of nrf-2 -mediated antioxidative enzymes and hsps in Puntius sophore
作者: Arabinda MahantySasmita MohantyBimal P. Mohanty
作者单位: 1ICAR - Central Inland Fisheries Research Institute
2KIIT University
刊名: Fish Physiology and Biochemistry, 2017, Vol.43 (4), pp.1131-1141
来源数据库: Springer Nature Journal
DOI: 10.1007/s10695-017-0358-z
关键词: Heat stressNrf-2Antioxidative enzymesHsp genesCurcuminPuntius sophore
原始语种摘要: Heat stress is one of the major environmental concerns in global warming regime and rising temperature has resulted in mass mortalities of animals including fishes. Therefore, strategies for high temperature stress tolerance and ameliorating the effects of heat stress are being looked for. In an earlier study, we reported that Nrf-2 (nuclear factor E2-related factor 2) mediated upregulation of antioxidative enzymes and heat shock proteins (Hsps) provide survivability to fish under heat stress. In this study, we have evaluated the ameliorative potential of dietary curcumin, a potential Nrf-2 inducer in heat stressed cyprinid Puntius sophore . Fishes were fed with diet supplemented with 0.5, 1.0, and 1.5% curcumin at the rate 2% of body weight daily in three separate groups ( n = 40 in each...
全文获取路径: Springer Nature  (合作)
影响因子:1.545 (2012)

  • curcumin 姜黄色素
  • stress 应力
  • enzymes 酶类
  • catalase 过氧化氢酶
  • ameliorative 改良的
  • shocked 受冲击的
  • basal 基部
  • tolerance 耐性
  • expression 表示
  • observed 观察到的