The effect of MElatonin on Depressive symptoms, Anxiety, CIrcadian and Sleep disturbances in patients after acute coronary syndrome (MEDACIS): study protocol for a randomized controlled trial
作者: Michael Tvilling MadsenAnders IsbrandUlla Overgaard AndersenLars Juel AndersenMustafa TaskiranErik SimonsenIsmail Gögenur
作者单位: 1University of Copenhagen
2Zealand University Hospital
3Holbaek Hospital
4Psychiatric Research Unit, Region Zealand
刊名: Trials, 2017, Vol.18 (1)
来源数据库: Springer Journal
DOI: 10.1186/s13063-017-1806-x
关键词: DepressionMelatoninAcute coronary syndromeAnxietySleep disturbancesCircadian rhythm
英文摘要: Depression following acute coronary syndrome (ACS) constitutes a serious and debilitating problem. Approximately one in five patients will develop significant depression following ACS and less severe depressive symptoms are even more frequent. Furthermore, anxiety symptoms and sleep-wake disturbances are frequent. The objective of the MEDACIS trial is to investigate whether prophylactic treatment with melatonin has a preventive effect on depression, depressive and anxiety symptoms, sleep, and circadian disturbances following ACS.
原始语种摘要: Depression following acute coronary syndrome (ACS) constitutes a serious and debilitating problem. Approximately one in five patients will develop significant depression following ACS and less severe depressive symptoms are even more frequent. Furthermore, anxiety symptoms and sleep-wake disturbances are frequent. The objective of the MEDACIS trial is to investigate whether prophylactic treatment with melatonin has a preventive effect on depression, depressive and anxiety symptoms, sleep, and circadian disturbances following ACS.
全文获取路径: Springer  (合作)
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来源刊物:
影响因子:2.206 (2012)

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关键词翻译
关键词翻译
  • coronary 冠状的
  • depressive 降低的
  • effect 效应
  • trial 试验
  • controlled 受控
  • depression 低地
  • sleep 睡眠
  • ACS Accounting Control System
  • syndrome 症候群
  • rhythm 韵律