Diagnostic value of the dual-luciferase report assay for predicting response to glucocorticoid in children with acute lymphoblastic leukemia
作者: X. WangP. ChenY. SunY. ChenM. MaoT. JiangJ. Ouyang
作者单位: 1Sun Yat-sen University Cancer Center
2The First Affiliated Hospital of Sun Yat-sen University
刊名: Clinical and Translational Oncology, 2017, Vol.19 (10), pp.1241-1246
来源数据库: Springer Journal
DOI: 10.1007/s12094-017-1661-y
关键词: GlucocorticoidDual-luciferase report assayAcute lymphoblastic leukemiaPrognosis
英文摘要: Resistance to glucocorticoid (GC) is a significant clinical problem in some cases of acute lymphoblastic leukemia (ALL). Current methods of assessing GC resistance are time consuming and have limited reproducibility; in this study, we sought to define a new method of evaluating GC sensitivity and resistance in vitro.
原始语种摘要: Resistance to glucocorticoid (GC) is a significant clinical problem in some cases of acute lymphoblastic leukemia (ALL). Current methods of assessing GC resistance are time consuming and have limited reproducibility; in this study, we sought to define a new method of evaluating GC sensitivity and resistance in vitro.
全文获取路径: Springer  (合作)
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影响因子:1.276 (2012)

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关键词翻译
关键词翻译
  • lymphoblastic 成淋巴细胞的
  • leukemia 白血病
  • luciferase 荧光素酶
  • acute 急尖的
  • glucocorticoid 糖皮质激素
  • assay 试金
  • report 通报
  • predicting 预测
  • consuming 耗的
  • response 响应