A turn-on fluorescent lysine nanoprobe based on the use of the Alizarin Red aluminum(III) complex conjugated to graphene oxide, and its application to cellular imaging of lysine
作者: Rumei ChengYu PengCongcong GeYexu BuHongyan LiuHuiying HuangShengju OuYuhua XueLiming Dai
作者单位: 1Wenzhou Medical University
2Zhejiang University National Science Park
3Case Western Reserve University
刊名: Microchimica Acta, 2017, Vol.184 (9), pp.3521-3528
来源数据库: Springer Journal
DOI: 10.1007/s00604-017-2375-0
关键词: Graphene oxideAlizarin redLysineAluminum complexPhotoinduced electron transfer
英文摘要: The authors describe a rationally designed nanoprobe for the fluorometric determination of lysine. It is based on a ternary complex consisting of graphene oxide, aluminum ions (acting as a bridging agent), and alizarin red (GO-Al-AR). The fluorescence of the complex (with excitation/emission maxima at 440/512 nm) is weak but significantly enhanced upon the addition of lysine, probably due to a photoinduced electron transfer signalling mechanism. The method has a detection limit of 2 mg L−1 of lysine and a linear range from 25 mg L−1 to 250 mg L−1. It was applied to image lysine in human retinal pigment epithelium cells.
原始语种摘要: The authors describe a rationally designed nanoprobe for the fluorometric determination of lysine. It is based on a ternary complex consisting of graphene oxide, aluminum ions (acting as a bridging agent), and alizarin red (GO-Al-AR). The fluorescence of the complex (with excitation/emission maxima at 440/512 nm) is weak but significantly enhanced upon the addition of lysine, probably due to a photoinduced electron transfer signalling mechanism. The method has a detection limit of 2 mg L−1 of lysine and a linear range from 25 mg L−1 to 250 mg L−1. It was applied to image lysine in human retinal pigment epithelium cells.
全文获取路径: Springer  (合作)
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来源刊物:
影响因子:3.434 (2012)

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关键词翻译
关键词翻译
  • lysine 赖氨酸
  • fluorescent 萤光的
  • complex 超群
  • aluminum 
  • rationally 理性上
  • oxide 氧化物
  • addition 添加
  • fluorometric 荧光的
  • signalling 发信号
  • electron 电子