Histogram analysis of amide proton transfer–weighted imaging: comparison of glioblastoma and solitary brain metastasis in enhancing tumors and peritumoral regions
作者: Kiyohisa KamimuraMasanori NakajoTomohide YoneyamaYoshihiko FukukuraHirofumi HiranoYuko GotoMasashi SasakiYuta AkamineJochen KeuppTakashi Yoshiura
作者单位: 1Department of Radiology, Kagoshima University Graduate School of Medical and Dental Sciences
2Department of Neurosurgery, Kagoshima University Graduate School of Medical and Dental Sciences
3Department of Pathology, Kagoshima University Graduate School of Medical and Dental Sciences
4Department of Radiological Technology, Kagoshima University Hospital
5Philips Japan
6Philips Research
刊名: European Radiology, 2019, Vol.29 (8), pp.4133-4140
来源数据库: Springer Journal
DOI: 10.1007/s00330-018-5832-1
关键词: GlioblastomaMetastasisMagnetic resonance imaging
英文摘要: Abstract(#br) Objectives(#br)Differentiation of glioblastomas (GBMs) and solitary brain metastases (SBMs) is an important clinical problem. The aim of this study was to determine whether amide proton transfer–weighted (APTW) imaging is useful for distinguishing GBMs from SBMs.(#br) Methods(#br)We examined 31 patients with GBM and 17 with SBM. For each tumor, enhancing areas (EAs) and surrounding non-enhancing areas with T2-prolongation (peritumoral high signal intensity areas, PHAs) were manually segmented using fusion images of the post-contrast T1-weighted and T2-weighted images. The mean amide proton transfer signal intensities (APTSIs) were compared among the EAs, PHAs, and contralateral normal appearing white matter (NAWM) within each tumor type. Furthermore, we analyzed APTSI...
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影响因子:3.548 (2012)

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