A missense variant in the coil1A domain of the keratin 25 gene is associated with the dominant curly hair coat trait (Crd) in horse
作者: Caroline MorgenthalerMathieu DiribarneAurélien CapitanRachel LegendreRomain SaintilanMaïlys GillesDiane EsquerréRytis JurasAnas KhanshourLaurent SchiblerGus Cothran
作者单位: 1INRA, AgroParisTech, Université Paris-Saclay
2ALLICE
3INRA
4Texas A&M University
5Texas Scottish Rite Hospital for Children
刊名: Genetics Selection Evolution, 2017, Vol.49 (1)
来源数据库: Springer Journal
DOI: 10.1186/s12711-017-0359-5
英文摘要: Curly horses present a variety of curl phenotypes that are associated with various degrees of curliness of coat, mane, tail and ear hairs. Their origin is still a matter of debate and several genetic hypotheses have been formulated to explain the diversity in phenotype, including the combination of autosomal dominant and recessive alleles. Our purpose was to map the autosomal dominant curly hair locus and identify the causal variant using genome-wide association study (GWAS) and whole-genome sequencing approaches.
原始语种摘要: Curly horses present a variety of curl phenotypes that are associated with various degrees of curliness of coat, mane, tail and ear hairs. Their origin is still a matter of debate and several genetic hypotheses have been formulated to explain the diversity in phenotype, including the combination of autosomal dominant and recessive alleles. Our purpose was to map the autosomal dominant curly hair locus and identify the causal variant using genome-wide association study (GWAS) and whole-genome sequencing approaches.
全文获取路径: Springer  (合作)
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来源刊物:
影响因子:2.859 (2012)

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关键词翻译
关键词翻译
  • dominant 优势的
  • locus 轨迹
  • recessive 隐性
  • variety 变种
  • trait 性状
  • curliness 卷曲度
  • associated 相关的
  • alleles 对立形质
  • horses 马类
  • variant 变体