Laser peripheral iridotomy versus laser peripheral iridotomy plus laser peripheral iridoplasty in the treatment of multi-mechanism angle closure: study protocol for a randomized controlled trial
作者: Shida ChenJianhua LvSujie FanHong ZhangLin XieLing XuBing JiangHuipin YuanYuanbo LiangShuning LiPingyan ChenXiulan ZhangNingli Wangfor the Multi-mechanism Angle Closure Study (MACs) group
作者单位: 1Sun Yat-sen University
2Hebei Provincial Eye Hospital
3Handan Eye Hospital
4Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
5The Third Military Medical University
6Liaoning He University, He Eye Hospital
7Central South University
8the Second Affiliated Hospital of Harbin Medical University
9the Affiliated Eye Hospital of Wenzhou Medical University
10Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Science Key Laboratory
11Southern Medical University
刊名: Trials, 2017, Vol.18 (1)
来源数据库: Springer Journal
DOI: 10.1186/s13063-017-1860-4
关键词: PACPACGPrimary angle closureLaser peripheral iridoplastyLaser peripheral iridotomyLPILPIPPrimary angle-closure glaucoma
英文摘要: China has the largest burden of primary angle-closure glaucoma (PACG) worldwide. The mechanism of the angle closure is complex and includes pupillary block and non-pupillary block. Currently, opinion is that laser peripheral iridotomy (LPI) alone is not sufficient to prevent disease progression. Laser peripheral iridoplasty (LPIP) is an alternative and effective way of widening the angle recess in eyes that are affected by primary angle closure (PAC). However, it is not known if greater benefit would be achieved using LPI plus LPIP for PAC with multiple mechanisms (MAC). Thus, the aim of this study is to demonstrate if LPI plus LPIP would be more effective than single LPI in controlling the progression of PAC with multiple mechanisms, based on ultrasound biomicroscopy (UBM)...
原始语种摘要: China has the largest burden of primary angle-closure glaucoma (PACG) worldwide. The mechanism of the angle closure is complex and includes pupillary block and non-pupillary block. Currently, opinion is that laser peripheral iridotomy (LPI) alone is not sufficient to prevent disease progression. Laser peripheral iridoplasty (LPIP) is an alternative and effective way of widening the angle recess in eyes that are affected by primary angle closure (PAC). However, it is not known if greater benefit would be achieved using LPI plus LPIP for PAC with multiple mechanisms (MAC). Thus, the aim of this study is to demonstrate if LPI plus LPIP would be more effective than single LPI in controlling the progression of PAC with multiple mechanisms, based on ultrasound biomicroscopy (UBM)...
全文获取路径: Springer  (合作)
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来源刊物:
影响因子:2.206 (2012)

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关键词翻译
关键词翻译
  • iridotomy 虹膜切开术
  • iridoplasty 虹膜成形术
  • closure 闭合
  • peripheral 周边的
  • angle 
  • glaucoma 绿内障
  • biomicroscopy 活组织显微镜检查
  • laser 激光
  • pupillary 小学生的
  • trial 试验