MiR-486 regulates cardiomyocyte apoptosis by p53-mediated BCL-2 associated mitochondrial apoptotic pathway
作者: Yuhan SunQiang SuLang LiXiantao WangYuanxi LuJiabao Liang
作者单位: 1The First Affiliated Hospital of Guangxi Medical University
刊名: BMC Cardiovascular Disorders, 2017, Vol.17 (1)
来源数据库: Springer Journal
DOI: 10.1186/s12872-017-0549-7
关键词: CardiomyocyteApoptosisMiR-486P53BCL-2 pathway
英文摘要: Cardiomyocyte apoptosis is a common pathological manifestation that occurs in several heart diseases. This study aimed to explore the mechanism of microRNA-486 (miR-486) in cardiomyocyte apoptosis by interfering with the p53-activated BCL-2 associated mitochondrial pathway.
原始语种摘要: Cardiomyocyte apoptosis is a common pathological manifestation that occurs in several heart diseases. This study aimed to explore the mechanism of microRNA-486 (miR-486) in cardiomyocyte apoptosis by interfering with the p53-activated BCL-2 associated mitochondrial pathway.
全文获取路径: Springer  (合作)
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来源刊物:
影响因子:1.457 (2012)

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关键词翻译
关键词翻译
  • pathway 轨道
  • associated 相关的
  • apoptosis 细胞死
  • mitochondrial 线粒体的
  • interfering 干涉
  • manifestation 特枕示
  • pathological 病理学的
  • several 各自
  • mechanism 机构
  • common 普通