Removal of the product from the culture medium strongly enhances free fatty acid production by genetically engineered Synechococcus elongatus
作者: Akihiro KatoNobuyuki TakataniKazutaka IkedaShin-ichi MaedaTatsuo Omata
作者单位: 1Nagoya University
2Japan Science and Technology Agency, CREST
3RIKEN Center for Integrative Medical Sciences
刊名: Biotechnology for Biofuels, 2017, Vol.10 (1)
来源数据库: Springer Journal
DOI: 10.1186/s13068-017-0831-z
关键词: CyanobacteriaBiofuel productionFree fatty acidsTwo-phase culture system
英文摘要: Cyanobacterial mutants engineered for production of free fatty acids (FFAs) secrete the products to the medium and hence are thought to be useful for biofuel production. The dAS1T mutant constructed from Synechococcus elongatus PCC 7942 has indeed a large capacity of FFA production, which is comparable to that of triacylglycerol production in green algae, but the yield of secreted FFAs is low because the cells accumulate most of the FFAs intracellularly and eventually die of their toxicity. To increase the FFA productivity, enhancement of FFA secretion is required.
原始语种摘要: Cyanobacterial mutants engineered for production of free fatty acids (FFAs) secrete the products to the medium and hence are thought to be useful for biofuel production. The dAS1T mutant constructed from Synechococcus elongatus PCC 7942 has indeed a large capacity of FFA production, which is comparable to that of triacylglycerol production in green algae, but the yield of secreted FFAs is low because the cells accumulate most of the FFAs intracellularly and eventually die of their toxicity. To increase the FFA productivity, enhancement of FFA secretion is required.
全文获取路径: Springer  (合作)
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来源刊物:
影响因子:5.552 (2012)

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关键词翻译
关键词翻译
  • production 生产
  • culture 
  • fatty 脂肪的
  • Synechococcus synechococcus属
  • system 
  • products 制品
  • engineered 设计的
  • their 他们的
  • medium 介质
  • because 由干