miR-17-5p suppresses cell proliferation and invasion by targeting ETV1 in triple-negative breast cancer
作者: Jie LiYuanhui LaiJieyi MaYue LiuJiong BiLongjuan ZhangLianzhou ChenChen YaoWeiming LvGuangqi ChangShenming WangMao OuyangWenjian Wang
作者单位: 1First Affiliated Hospital of Sun Yat-sen University
2Thyroid and Breast Surgery, First Affiliated Hospital of Sun Yat-sen University
3Thyroid and Breast Surgery, Eastern Hospital of the First Affiliated Hospital of Sun Yat-sen University
4Centre for Cellular & Structural biology, School of Pharmaceutical Sciences of Sun Yat-Sen University
5First Affiliated Hospital of Sun Yat-sen
刊名: BMC Cancer, 2017, Vol.17 (1)
来源数据库: Springer Nature Journal
DOI: 10.1186/s12885-017-3674-x
关键词: MiR-17-5pETV1Triple-negative breast cancer
原始语种摘要: Triple-negative breast cancer (TNBC) is the malignancy with the worst outcome among all breast cancer subtypes. We reported that ETV1 is a significant oncogene in TNBC tumourigenesis. Consequently, investigating the critical regulatory microRNAs (miRNAs) of ETV1 may be beneficial for TNBC targeted therapy.
全文获取路径: Springer Nature  (合作)
影响因子:3.333 (2012)

  • breast 胸部
  • targeting 导向目标
  • cancer 癌症
  • tumourigenesis 致肿瘤性
  • invasion 侵入
  • malignancy 恶性
  • negative 负象
  • targeted 对准目标的
  • proliferation 增生
  • oncogene 肿瘤基因