Whole-genome association analysis of pork meat pH revealed three significant regions and several potential genes in Finnish Yorkshire pigs
作者: Lucas L. VerardoMarja-Liisa Sevón-AimonenTimo SereniusVille HietakangasPekka Uimari
作者单位: 1Federal University of Viçosa
2Green technology, Natural Resources Institute Finland
3Figen Oy
4University of Helsinki
刊名: BMC Genetics, 2017, Vol.18 (1)
来源数据库: Springer Journal
DOI: 10.1186/s12863-017-0482-x
关键词: Association analysisMeat qualityPigPost-GWAS analysis
英文摘要: One of the most commonly used quality measurements of pork is pH measured 24 h after slaughter. The most probable mode of inheritance for this trait is oligogenic with several known major genes, such as PRKAG3 . In this study, we used whole-genome SNP genotypes of over 700 AI boars; after a quality check, 42,385 SNPs remained for association analysis. All the boars were purebred Finnish Yorkshire. To account for relatedness of the animals, a pedigree-based relationship matrix was used in a mixed linear model to test the effect of SNPs on pH measured from loin. A bioinformatics analysis was performed to identify the most promising genes in the significant regions related to meat quality.
原始语种摘要: One of the most commonly used quality measurements of pork is pH measured 24 h after slaughter. The most probable mode of inheritance for this trait is oligogenic with several known major genes, such as PRKAG3 . In this study, we used whole-genome SNP genotypes of over 700 AI boars; after a quality check, 42,385 SNPs remained for association analysis. All the boars were purebred Finnish Yorkshire. To account for relatedness of the animals, a pedigree-based relationship matrix was used in a mixed linear model to test the effect of SNPs on pH measured from loin. A bioinformatics analysis was performed to identify the most promising genes in the significant regions related to meat quality.
全文获取路径: Springer  (合作)
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影响因子:2.808 (2012)

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关键词翻译
关键词翻译
  • analysis 分析
  • several 各自
  • genome 基因组
  • significant 有效的
  • oligogenic 寡基因的
  • pedigree 谱系图
  • quality 品质
  • potential 
  • bioinformatics 生物信息学
  • association 联合