A fragment based method for modeling of protein segments into cryo-EM density maps
作者: Jochen IsmerAlexander S. RoseJohanna K. S. TiemannPeter W. Hildebrand
作者单位: 1University Medicine Berlin
2University of California
3University Leipzig
刊名: BMC Bioinformatics, 2017, Vol.18 (1)
来源数据库: Springer Journal
DOI: 10.1186/s12859-017-1904-5
关键词: Cryo-EMFragment based modelingFlexible fitting
英文摘要: Single-particle analysis of electron cryo-microscopy (cryo-EM) is a key technology for elucidation of macromolecular structures. Recent technical advances in hardware and software developments significantly enhanced the resolution of cryo-EM density maps and broadened the applicability and the circle of users. To facilitate modeling of macromolecules into cryo-EM density maps, fast and easy to use methods for modeling are now demanded.
原始语种摘要: Single-particle analysis of electron cryo-microscopy (cryo-EM) is a key technology for elucidation of macromolecular structures. Recent technical advances in hardware and software developments significantly enhanced the resolution of cryo-EM density maps and broadened the applicability and the circle of users. To facilitate modeling of macromolecules into cryo-EM density maps, fast and easy to use methods for modeling are now demanded.
全文获取路径: Springer  (合作)
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来源刊物:
影响因子:3.024 (2012)

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关键词翻译
关键词翻译
  • modeling 制祝型
  • density 密度
  • software 软件
  • hardware 硬件
  • fitting 匹配
  • circle 
  • microscopy 显微镜检查
  • macromolecular 大分子的
  • method 方法
  • applicability 适用性