RNA sequencing reveals candidate genes and polymorphisms related to sperm DNA integrity in testis tissue from boars
作者: Maren van SonNina Hårdnes TremoenAnn Helen GaustadFrøydis Deinboll MyromslienDag Inge VågeElse-Berit StensethTeklu Tewoldebrhan ZeremichaelEli Grindflek
作者单位: 1Topigs Norsvin
2Inland Norway University of Applied Sciences
3Norwegian University of Life Sciences
刊名: BMC Veterinary Research, 2017, Vol.13 (1)
来源数据库: Springer Journal
DOI: 10.1186/s12917-017-1279-x
关键词: Transcriptome profilingSperm DNA integrityDifferential expression
英文摘要: Sperm DNA is protected against fragmentation by a high degree of chromatin packaging. It has been demonstrated that proper chromatin packaging is important for boar fertility outcome. However, little is known about the molecular mechanisms underlying differences in sperm DNA fragmentation. Knowledge of sequence variation influencing this sperm parameter could be beneficial in selecting the best artificial insemination (AI) boars for commercial production. The aim of this study was to identify genes differentially expressed in testis tissue of Norwegian Landrace and Duroc boars, with high and low sperm DNA fragmentation index (DFI), using transcriptome sequencing.
原始语种摘要: Sperm DNA is protected against fragmentation by a high degree of chromatin packaging. It has been demonstrated that proper chromatin packaging is important for boar fertility outcome. However, little is known about the molecular mechanisms underlying differences in sperm DNA fragmentation. Knowledge of sequence variation influencing this sperm parameter could be beneficial in selecting the best artificial insemination (AI) boars for commercial production. The aim of this study was to identify genes differentially expressed in testis tissue of Norwegian Landrace and Duroc boars, with high and low sperm DNA fragmentation index (DFI), using transcriptome sequencing.
全文获取路径: Springer  (合作)
分享到:
来源刊物:
影响因子:1.861 (2012)

×
关键词翻译
关键词翻译
  • sequencing 排序
  • sperm 精子
  • integrity 综合性
  • related 有关的
  • testis 睾丸
  • DNA Deoxyribonucleic Acid
  • chromatin 染色质
  • tissue 组织
  • RNA ROYAL NEPAL AIRLINES CORP.
  • expression 表示