Dopamine D1-D5 receptor protein immunohistochemistry in dog pial arteries
作者: Francesco AmentaRoberto AvolaElena BronzettiLaura FeliciGiovanni GermanàFiorenzo MigniniAlberto RicciMaurizio Sabbatini
作者单位: 1Section of Human Anatomy, Department of Pharmacological Sciences and Experimental Medicine, University of Camerino, Via Scalzino 3, I-62032 Camerino, Italy, e-mail:, Tel.: +39-0737-403311, Fax: +39-0737-630618
2Section of Biochemistry, Department of Chemistry, University of Catania, Catania, Italy
3Department of Cardiovascular and Respiratory Sciences, University La Sapienza, Rome, Italy
4Institute of Domestic Animal Anatomy, with Histology and Embriology, University of Messina, Messina, Italy
刊名: The Journal of Headache and Pain, 2000, Vol.1 (3), pp.163-168
来源数据库: Springer Nature Journal
DOI: 10.1007/s101940070038
关键词: Key words Dopamine receptorsPial arteriesImmunohistochemistryPrejunctional receptorsPost-junctional receptors
英文摘要: Abstract(#br) The localization of dopamine D1-D5 receptor protein was investigated in different sized dog pial arteries. This was done to further understand the pathophysiology of cerebrovascular dopaminergic system in migraine. The study was performed in sections of dog brain including the pia-arachnoid membrane, which were processed for indirect immunohistochemistry using antibodies raised against dopamine D1-D5 receptor protein. A faint dopamine D1 receptor protein immunoreactivity was observed in smooth muscle of the tunica media of different sized pial arteries. Dopamine D2 receptor protein immunoreactivity was located in the adventitia and adventitia-media border of pial arteries. In the same area tyrosine hydroxylase immunoreactive nerve fibers were found. No dopamine D3 receptor...
全文获取路径: Springer Nature  (合作)
影响因子:2.779 (2012)

  • protein 蛋白质
  • receptor 接受体