Pain-relieving effects of intravenous ATP in chronic intractable orofacial pain: an open-label study
作者: Ken-ichi FukudaMasakazu HayashidaAtsuo FukunagaMasataka KasaharaYoshihiko KoukitaTatsuya IchinoheYuzuru Kaneko
作者单位: 1Department of Dental Anesthesia and Orofacial Pain Center, Tokyo Dental College, Suidoubashi Hospital
2Surgical Center Research Hospital, The Institute of Medical Science, The University of Tokyo
3Professor Emeritus, Department of Anesthesiology, UCLA
4Department of Dental Anesthesiology, Tokyo Dental College
刊名: Journal of Anesthesia, 2007, Vol.21 (1), pp.24-30
来源数据库: Springer Nature Journal
DOI: 10.1007/s00540-006-0444-3
关键词: Adenosine triphosphate (ATP)Neuropathic painPostherpetic neuralgiaPulpectomyTooth extraction
英文摘要: Abstract(#br) Purpose(#br)Chronic orofacial pain is often refractory to conventional pain therapies. We conducted an open-label study to determine whether adenosine 5′-triphosphate (ATP) could alleviate chronic intractable orofacial pain, and if so, which type of pain could respond to ATP.(#br) Methods(#br)In 8 and 16 patients with non-neuropathic and neuropathic intractable orofacial pain, respectively, ATP was intravenously infused at a rate of 100 µg·kg −1 ·min −1 over 120 min. The magnitudes of spontaneous pain and brush-evoked allodynia were graded with a visual analog scale (VAS). When a VAS score for spontaneous pain was decreased by 50% or more by ATP, the patient was classified as a responder.(#br) Results(#br)The patients could be clearly divided into 10 responders and 14...
全文获取路径: Springer Nature  (合作)
影响因子:0.867 (2012)

  • intractable 不治的
  • relieving 
  • label 标签标记
  • intravenous 静脉内的
  • chronic 延续很长的
  • ATP Acceptance Test Procedure
  • effects 海员自身物品
  • study 学习