Water extract of Rumex crispus prevents bone loss by inhibiting osteoclastogenesis and inducing osteoblast mineralization
作者: Ki-Shuk ShimBohyoung LeeJin Yeul Ma
作者单位: 1KM Application Center, Korea Institute of Oriental Medicine
刊名: BMC Complementary and Alternative Medicine, 2017, Vol.17 (1)
来源数据库: Springer Nature Journal
DOI: 10.1186/s12906-017-1986-7
关键词: Rumex crispusBone lossOsteoblastOsteoclastRunx2Nuclear factor of activated T cells cytoplasmic 1
英文摘要: Rumex crispus root has traditionally been used in Asian medicine for the treatment of hemorrhage and dermatolosis. The aim of this study was to explore the pharmaceutical effects of water extract of Rumex crispus (WERC) on osteoblast and osteoclast differentiation. We also studied the effect of WERC on the receptor activator of nuclear factor kappa-B ligand (RANKL)-induced trabecular bone destruction mice model.
原始语种摘要: Rumex crispus root has traditionally been used in Asian medicine for the treatment of hemorrhage and dermatolosis. The aim of this study was to explore the pharmaceutical effects of water extract of Rumex crispus (WERC) on osteoblast and osteoclast differentiation. We also studied the effect of WERC on the receptor activator of nuclear factor kappa-B ligand (RANKL)-induced trabecular bone destruction mice model.
全文获取路径: Springer Nature  (合作)
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来源刊物:
影响因子:2.082 (2012)

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关键词翻译
关键词翻译
  • osteoblast 成骨细胞
  • inhibiting 抑制
  • crispus 皱缘
  • Osteoclast 破骨细胞
  • osteoclast 破骨细胞
  • extract 提取
  • factor 因素
  • cytoplasmic 细胞质的
  • activator 活化剂
  • induced 感应的