Poor prognosis of patients with triple-negative breast cancer can be stratified by RANK and RANKL dual expression
作者: Monica E. ReyesTakeo FujiiDaniel BranstetterSavitri KrishnamurthyHiroko MasudaXiaoping WangJames M. ReubenWendy A. WoodwardBeatrice J. EdwardsGabriel N. HortobagyiDebu TripathyWilliam C. DougallBedrich L. EckhardtNaoto T. Ueno
作者单位: 1The University of Texas MD Anderson Cancer Center
2The University of Texas Health Science Center at Houston School of Public Health
3Amgen, Inc.
4The Univers
刊名: Breast Cancer Research and Treatment, 2017, Vol.164 (1), pp.57-67
来源数据库: Springer Nature Journal
DOI: 10.1007/s10549-017-4233-5
关键词: Triple-negative breast cancerRANKRANKLRelapse-free survivalOverall survival
原始语种摘要: As clinical studies have correlated RANK expression levels with survival in breast cancer, and that RANK signaling is dependent on its cognate ligand RANKL, we hypothesized that dual protein expression further stratifies the poor outcome in TNBC.
全文获取路径: Springer Nature  (合作)
影响因子:4.469 (2012)

  • breast 胸部
  • prognosis 预报
  • survival 生存
  • expression 表示
  • cancer 癌症
  • correlated 相关
  • triple 三重的
  • outcome 效果
  • signaling 发信号
  • dependent 从属的