Post-resistance exercise ingestion of milk protein attenuates plasma TNFα and TNFr1 expression on monocyte subpopulations
作者: Adam J. WellsAdam R. JajtnerAlyssa N. VaranoskeDavid D. ChurchAdam M. GonzalezJeremy R. TownsendCarleigh H. BooneKayla M. BakerKyle S. BeyerGerald T. MangineLeonardo P. OliveiraDavid H. FukudaJeffrey R. StoutJay R. Hoffman
作者单位: 1University of Central Florida
2Kent State University
3Hofstra University
4Lipscomb University
5Kennesaw State University
6University of Chicago Medical Center
刊名: Amino Acids, 2017, Vol.49 (8), pp.1415-1426
来源数据库: Springer Nature Journal
DOI: 10.1007/s00726-017-2443-0
关键词: InflammationTumor necrosis factor-alpha (TNFα)Tumor necrosis factor receptor 1 (TNFr1)Classical monocytesIntermediate monocytesNon-classical monocytes
英文摘要: Attenuating TNFα/TNFr1 signaling in monocytes has been proposed as a means of mitigating inflammation. The purpose of this study was to examine the effects of a milk protein supplement on TNFα and monocyte TNFr1 expression. Ten resistance-trained men (24.7 ± 3.4 years; 90.1 ± 11.3 kg; 176.0 ± 4.9 cm) ingested supplement (SUPP) or placebo (PL) immediately post-exercise in a randomized, cross-over design. Blood samples were obtained at baseline (BL), immediately (IP), 30-min (30P), 1-h (1H), 2-h (2H), and 5-h (5H) post-exercise to assess plasma concentrations of myoglobin; tumor necrosis factor-alpha (TNFα); and expression of tumor necrosis factor receptor 1 (TNFr1) on classical, intermediate, and non-classical monocytes. Magnitude-based inferences were used to provide inferences on the...
原始语种摘要: Attenuating TNFα/TNFr1 signaling in monocytes has been proposed as a means of mitigating inflammation. The purpose of this study was to examine the effects of a milk protein supplement on TNFα and monocyte TNFr1 expression. Ten resistance-trained men (24.7 ± 3.4 years; 90.1 ± 11.3 kg; 176.0 ± 4.9 cm) ingested supplement (SUPP) or placebo (PL) immediately post-exercise in a randomized, cross-over design. Blood samples were obtained at baseline (BL), immediately (IP), 30-min (30P), 1-h (1H), 2-h (2H), and 5-h (5H) post-exercise to assess plasma concentrations of myoglobin; tumor necrosis factor-alpha (TNFα); and expression of tumor necrosis factor receptor 1 (TNFr1) on classical, intermediate, and non-classical monocytes. Magnitude-based inferences were used to provide inferences on the...
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影响因子:3.914 (2012)

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关键词翻译
关键词翻译
  • expression 表示
  • exercise 练习
  • immediately 立即
  • protein 蛋白质
  • likelihood 似然
  • likely 大概
  • effect 效应
  • classical 经典的
  • factor 因素
  • examine