Bone mineral density of extremities is associated with coronary calcification and biopsy-verified vascular calcification in living-donor renal transplant recipients
作者: Zhimin ChenJia SunMathias HaarhausPeter BaranyLars WennbergJonaz RipswedenTorkel B. BrismarBengt LindholmAnnika WernersonMagnus SöderbergPeter StenvinkelAbdul Rashid Qureshi
作者单位: 1Karolinska Institutet
21st Affiliated Hospital College of Medicine, Zhejiang University
3CLINTEC, Karolinska Institutet
4AstraZeneca
刊名: Journal of Bone and Mineral Metabolism, 2017, Vol.35 (5), pp.536-543
来源数据库: Springer Nature Journal
DOI: 10.1007/s00774-016-0788-1
关键词: Bone mineral densityCoronary artery calciumVascular calcificationLiving-donor renal transplant recipientsEnd-stage renal disease
英文摘要: Chronic kidney disease (CKD) mineral and bone disorders (CKD-MBD) may lead to low bone mineral density (BMD) and vascular calcification (VC), but links to the latter are unclear. Here we investigated associations between BMD, coronary artery calcium (CAC) scores, and histological signs of VC in end-stage renal disease (ESRD) patients undergoing living-donor kidney transplantation (LD-Rtx). In 66 ESRD patients (median age 45 years, 68% males), BMD (by dual-energy X-ray absorptiometry, DXA), CAC score (by computed tomography, CT; n = 54), and degree of VC score (graded by histological examination of epigastric artery specimens collected at LD-Rtx; n = 55) were assessed at the time of LD-Rtx. Of the patients, 26% had osteopenia and 7% had osteoporosis. Of those undergoing artery biopsy, 16%...
原始语种摘要: Chronic kidney disease (CKD) mineral and bone disorders (CKD-MBD) may lead to low bone mineral density (BMD) and vascular calcification (VC), but links to the latter are unclear. Here we investigated associations between BMD, coronary artery calcium (CAC) scores, and histological signs of VC in end-stage renal disease (ESRD) patients undergoing living-donor kidney transplantation (LD-Rtx). In 66 ESRD patients (median age 45 years, 68% males), BMD (by dual-energy X-ray absorptiometry, DXA), CAC score (by computed tomography, CT; n = 54), and degree of VC score (graded by histological examination of epigastric artery specimens collected at LD-Rtx; n = 55) were assessed at the time of LD-Rtx. Of the patients, 26% had osteopenia and 7% had osteoporosis. Of those undergoing artery biopsy, 16%...
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来源刊物:
影响因子:2.219 (2012)

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关键词翻译
关键词翻译
  • calcification 钙化
  • renal 肾的
  • donor 给予体
  • density 密度
  • associated 相关的
  • coronary 冠状的
  • transplant 移植体
  • vascular 维管的
  • mineral 矿物
  • living 生存的