Administration of HES in elderly patients undergoing hip arthroplasty under spinal anesthesia is not associated with an increase in renal injury
作者: Yuanyuan ZhangYonghao YuJunya JiaWenli YuRubin XuLicheng GengYing Wei
作者单位: 1Tianjin Medical University General Hospital
2Tianjin Research Institute of Anaesthesiology
3Tianjin First Central Hospital
4Tianjin People’s Hospital Tianjin Union Medical Center
刊名: BMC Anesthesiology, 2017, Vol.17 (1)
来源数据库: Springer Nature Journal
DOI: 10.1186/s12871-017-0320-8
关键词: Acute kidney injuryElderly patientsHydroxyethyl starchIL-18NGAL
英文摘要: Hydroxyethyl starch (HES) is applied to achieve volume expansion during surgery; however, nephrotoxicity may be induced in patients with sepsis. Simultaneously, neutrophil gelatinase-associated lipocalin (NGAL) and IL-18 have been illustrated as pivotal indicators to diagnose the acute kidney injury (AKI) early. This multi-center, randomized, double-blinded, placebo-controlled study aimed to investigate whether 6% HES 130/0.4 administration caused postoperative AKI, which can be revealed by urinary and plasma NGAL and IL-18 estimations in elderly patients with normal renal function undergoing hip arthroplasty under spinal anesthesia.
原始语种摘要: Hydroxyethyl starch (HES) is applied to achieve volume expansion during surgery; however, nephrotoxicity may be induced in patients with sepsis. Simultaneously, neutrophil gelatinase-associated lipocalin (NGAL) and IL-18 have been illustrated as pivotal indicators to diagnose the acute kidney injury (AKI) early. This multi-center, randomized, double-blinded, placebo-controlled study aimed to investigate whether 6% HES 130/0.4 administration caused postoperative AKI, which can be revealed by urinary and plasma NGAL and IL-18 estimations in elderly patients with normal renal function undergoing hip arthroplasty under spinal anesthesia.
全文获取路径: Springer Nature  (合作)
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来源刊物:
影响因子:1.188 (2012)

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关键词翻译
关键词翻译
  • anesthesia 感觉缺失
  • arthroplasty 关节成形术
  • renal 肾的
  • elderly 上了年纪的
  • associated 相关的
  • injury 损害
  • spinal 脊柱的
  • postoperative 手术后的
  • nephrotoxicity 中毒性肾损害
  • kidney 肾脏