Video approach to chemiluminescence detection using a low-cost complementary metal oxide semiconductor (CMOS)-based camera: determination of paracetamol in pharmaceutical formulations
作者: Luis Lahuerta-ZamoraAna M. Mellado-Romero
作者单位: 1Universidad CEU-Cardenal Herrera
2Universitat Politècnica de València
刊名: Analytical and Bioanalytical Chemistry, 2017, Vol.409 (15), pp.3891-3898
来源数据库: Springer Nature Journal
DOI: 10.1007/s00216-017-0334-6
关键词: Flow chemiluminescenceCMOS cameraImageJPharmaceutical analysis
原始语种摘要: A new system for continuous flow chemiluminescence detection, based on the use of a simple and low-priced lens-free digital camera (with complementary metal oxide semiconductor technology) as a detector, is proposed for the quantitative determination of paracetamol in commercial pharmaceutical formulations. Through the camera software, AVI video files of the chemiluminescence emission are captured and then, using friendly ImageJ public domain software (from National Institutes for Health), properly processed in order to extract the analytical information. The calibration graph was found to be linear over the range 0.01–0.10 mg L−1 and over the range 1.0–100.0 mg L−1 of paracetamol, the limit of detection being 10 μg L−1. No significative interferences were...
全文获取路径: Springer Nature  (合作)
影响因子:3.659 (2012)

  • CMOS Complementary Metal-Oxide-Semiconductor
  • detection 探测
  • pharmaceutical 
  • paracetamol 4乙酰氨基酚
  • determination 测定
  • semiconductor 半导体
  • complementary 补的
  • significative 有意义的
  • software 软件
  • results 成果