Opening the Regulatory Black Box of Clinical Cancer Research: Transnational Expertise Networks and “Disruptive” Technologies
作者: Alberto CambrosioPascale BourretPeter KeatingNicole Nelson
作者单位: 1McGill University
2Aix Marseille Univ, INSERM, IRD, SESSTIM
3Université du Québec à Montréal
4University of Wisconsin-Madison
刊名: Minerva, 2017, Vol.55 (2), pp.161-185
来源数据库: Springer Nature Journal
DOI: 10.1007/s11024-017-9324-2
关键词: OncologyClinical cancer researchBiomedical regulationTransnational expertise networksCancer pathologyBiomarkers
原始语种摘要: Building on previous work on “regulatory objectivity,” the paper examines recent translational research and cancer genomics to explore the bundle of scientific and regulatory activities that generate and manage the platforms at the core of clinical trials, the “gold standard” of clinical research and evidence-based medicine. In particular, the paper explores the activities of a chain of mediators within a seamless regulatory web characterized by the interaction of endogenous and hybrid regulatory activities that are neither hierarchical nor linear. We contend that a full understanding of the dynamics of regulation in the biomedical domain ought to consider this chain of mediations; that their analysis necessitates understanding the content of the practices they regulate; and that in...
全文获取路径: Springer Nature  (合作)
影响因子:0.884 (2012)

  • Black 布莱克
  • expertise 专家评价
  • regulatory 控制的
  • routine 程序
  • their 他们的
  • regulation 
  • particular 细致的
  • development 开发
  • scientific 科学
  • between 在中间