Biomarkers of muscle quality: N-terminal propeptide of type III procollagen and C-terminal agrin fragment responses to resistance exercise training in older adults
作者: Maren S. FragalaAdam R. JajtnerKyle S. BeyerJeremy R. TownsendNadia S. EmersonTyler C. ScanlonLeonardo P. OliveiraJay R. HoffmanJeffrey R. Stout
作者单位: 1Institute of Exercise Physiology and Wellness, University of Central Florida
刊名: Journal of Cachexia, Sarcopenia and Muscle, 2014, Vol.5 (2), pp.139-148
来源数据库: Springer Nature Journal
DOI: 10.1007/s13539-013-0120-z
关键词: SarcopeniaMuscle qualityBiomarkersResistance exerciseNeuromuscular
原始语种摘要: Abstract(#br) Background(#br)N-terminal peptide of procollagen type III (P3NP) and C-terminal agrin fragment (CAF) are circulating biomarkers that are related to lean body mass in older adults. P3NP is a circulating marker reflective of muscular structural remodeling while CAF is a circulating marker of neuromuscular remodeling. As resistance exercise is an established intervention that can effectively improve muscle quality, we sought to evaluate circulating biomarker changes corresponding to a resistance exercise intervention in older adults.(#br) Methods(#br)Twenty-three older adults (aged 61 to 85 years) were randomized into an intervention (6-week resistance training) or control group. Resting circulating P3NP, CAF, lean body mass (LBM), muscle cross-sectional area (CSA), muscle...
全文获取路径: Springer Nature  (合作)
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关键词翻译
关键词翻译
  • terminal 顶端的
  • exercise 练习
  • muscle 肌肉
  • procollagen 酸溶胶原蛋白
  • fragment 碎屑
  • older 
  • training 培养
  • quality 品质
  • resistance 抵抗