Polyamines: therapeutic perspectives in oxidative stress and inflammatory diseases
作者: Tarique HussainBie TanWenkai RenNajma RahuRahim DadDildar Hussain KalhoroYulong Yin
作者单位: 1National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Key Laboratory of Agro-ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, Chinese Academy of Sciences
2University of the Chinese Academy of Sciences
3Sindh Agriculture University
4Huazhong Agricultural University
5National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Po
刊名: Amino Acids, 2017, Vol.49 (9), pp.1457-1468
来源数据库: Springer Nature Journal
DOI: 10.1007/s00726-017-2447-9
关键词: PolyaminesOxidative stressAnti-oxidantAnti-inflammatory properties
英文摘要: Polyamines are naturally occurring aliphatic compounds, particularly essential elements for biological functions. These compounds play a central role in regulating molecular pathways which are responsible for cellular proliferation, growth, and differentiation. Importantly, excessive polyamine catabolism can lead to a prominent source of oxidative stress which increases inflammatory response and thought to be involved in several diseases including stroke, renal failure, neurological disease, liver disease, and even cancer. Moreover, polyamine supplementation increases life span in model organisms and may encounter oxidative stress via exerting its potential anti-oxidant and anti-inflammatory properties. The revealed literature indicates that an emerging role of polyamine biosynthetic...
原始语种摘要: Polyamines are naturally occurring aliphatic compounds, particularly essential elements for biological functions. These compounds play a central role in regulating molecular pathways which are responsible for cellular proliferation, growth, and differentiation. Importantly, excessive polyamine catabolism can lead to a prominent source of oxidative stress which increases inflammatory response and thought to be involved in several diseases including stroke, renal failure, neurological disease, liver disease, and even cancer. Moreover, polyamine supplementation increases life span in model organisms and may encounter oxidative stress via exerting its potential anti-oxidant and anti-inflammatory properties. The revealed literature indicates that an emerging role of polyamine biosynthetic...
全文获取路径: Springer Nature  (合作)
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影响因子:3.914 (2012)

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关键词翻译
关键词翻译
  • stress 应力
  • polyamine 多聚胺
  • inflammatory 激怒的
  • oxidative 氧化的
  • oxidant 氧化剂
  • aliphatic 无环的
  • catabolism 分化酌
  • biosynthetic 生物合成
  • responsible 负责的
  • against 反对