A novel detection method of human serum albumin based on CuInZnS quantum dots-Co 2+ sensing system
作者: Wenying GuiXueqian ChenQiang Ma
作者单位: 1Jilin University
刊名: Analytical and Bioanalytical Chemistry, 2017, Vol.409 (15), pp.3871-3876
来源数据库: Springer Nature Journal
DOI: 10.1007/s00216-017-0332-8
关键词: CuInZnS QDsHuman serum albumin (HSA)“Turn off-on”Fluorescence assay
英文摘要: We developed a novel “turn off-on” sensor for human serum albumin (HSA) detection based on CuInZnS quantum dots (CIZS QDs). The photoluminescence (PL) of QDs can be “turned off” by Co(II) first. Because of the strong binding ability of HSA with Co2+, Co2+ can be removed from CIZS QDs with the addition of HSA. As a result, the PL of CIZS QDs probe can be “turned on” with an increased concentration of HSA over a wide range. The analyte HSA concentration had a proportional linear relationship with the recovered PL intensity of CIZS QDs. The detection limit for HSA was 4.5 × 10–8 mol L–1. The results indicated that the CIZS QDs- Co2+-BSA sensing system possessed higher sensitivity and better practicability for HSA detection.
原始语种摘要: We developed a novel “turn off-on” sensor for human serum albumin (HSA) detection based on CuInZnS quantum dots (CIZS QDs). The photoluminescence (PL) of QDs can be “turned off” by Co(II) first. Because of the strong binding ability of HSA with Co2+, Co2+ can be removed from CIZS QDs with the addition of HSA. As a result, the PL of CIZS QDs probe can be “turned on” with an increased concentration of HSA over a wide range. The analyte HSA concentration had a proportional linear relationship with the recovered PL intensity of CIZS QDs. The detection limit for HSA was 4.5 × 10–8 mol L–1. The results indicated that the CIZS QDs- Co2+-BSA sensing system possessed higher sensitivity and better practicability for HSA detection.
全文获取路径: Springer Nature  (合作)
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来源刊物:
影响因子:3.659 (2012)

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关键词翻译
关键词翻译
  • sensing system 感觉系统
  • novel 长篇小说
  • detection 探测
  • serum 血清
  • concentration 浓度
  • Fluorescence 荧光
  • recovered 恢复
  • albumin 白蛋白
  • quantum 量子
  • practicability 现实性