Cadmium Concentrations in Blood and Seminal Plasma: Correlations with Sperm Number and Motility in Three Male Populations (Infertility Patients, Artificial Insemination Donors, and Unselected Volunteers)
血液和精浆中的镉浓度:与三个男性群体(不育患者、人工授精捐献者和未经选择的志愿者)的精子数量和运动能力的关系
作者: Susan BenoffRuss HauserJoel L. MarmarIan R. HurleyBarbara NapolitanoGrace M. Centola
作者单位: 1Fertility Research Laboratories, The Feinstein Institute for Medical Research, 350 Community Drive, 11030, Manhasset, New York, USA
2Department of Obstetrics and Gynecology, North Shore University Hospital, North Shore-Long Island Jewish Health System, Manhasset, New York, USA
3Departments of Obstetrics and Gynecology and Cell Biology, New York University School of Medicine, New York, New York, USA
4Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA
5Vincent Memorial Obstetrics and Gynecology Service, Andrology Laboratory and In Vitro Fertilization Unit, Massachusetts General Hospital, Boston, Massachusetts, USA
6Division of Urology, Department of Surgery, Robert Wood Johnson Medical School, Camden, New Jersey, USA
7Biostatistics Unit, The Feinstein Institute for Medical Research, Manhasset, New York, USA
8Department of Obstetrics and Gynecology, University of Rochester Medical Center, Rochester, New York, USA
9New England Cryogenic Center, Newton, Massachusetts, U
刊名: Molecular Medicine, 2009, Vol.15 (Suppl1), pp.248-262
来源数据库: Springer Nature Journal
DOI: 10.2119/molmed.2008.00104
英文摘要: Abstract(#br)To investigate a possible common environmental exposure that may partially explain the observed decrease in human semen quality, we correlated seminal plasma and blood cadmium levels with sperm concentration and sperm motility. We studied three separate human populations: group 1, infertility patients (Long Island, NY, USA); group 2, artificial insemination donors (AID) (Rochester, NY, USA); and group 3, general population volunteers (Rochester, NY, USA). Information about confounding factors was collected by questionnaire. Seminal plasma cadmium did not correlate with blood cadmium (Spearman correlation, n = 91, r = −0.092, P = 0.386, NS). Both blood and seminal plasma cadmium were significantly higher among infertility patients than the other subjects studied (for example,...
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影响因子:4.469 (2012)

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