Bio-cellular processes modeling on silicon substrate: receptor–ligand binding and Michaelis Menten reaction
作者: Maria WaqasMuhammad KhurramS. M. Rezaul Hasan
作者单位: 1NED University of Engineering and Technology
2Massey University
刊名: Analog Integrated Circuits and Signal Processing, 2017, Vol.93 (2), pp.329-340
来源数据库: Springer Nature Journal
DOI: 10.1007/s10470-017-1044-x
关键词: Analog electronic circuit modelingBio-cellular systemsEnzymatic reactionsReceptor–ligand bindingMichaelis Menten kineticsVelocity saturated short channel MOS transistor
英文摘要: There has been a growing interest and motivation in analog electronic circuit modeling of bio-cellular networks, which forms the basis of cellular functions of all living organisms. The complexity and size of such networks has made this task arduous, while opening up new opportunities as well. A number of modeling techniques, from mathematical models to computer simulations, have been used in this domain to aid the interpretation of such complex and sophisticated networks. This research article focuses on modeling of bio-cellular structures and processes on silicon substrate using transistors in analog domain. MOS transistor analogies for some very commonly found bio-cellular reactions namely receptor–ligand kinetics and Michaelis Menten kinetics have been presented, which are based on...
原始语种摘要: There has been a growing interest and motivation in analog electronic circuit modeling of bio-cellular networks, which forms the basis of cellular functions of all living organisms. The complexity and size of such networks has made this task arduous, while opening up new opportunities as well. A number of modeling techniques, from mathematical models to computer simulations, have been used in this domain to aid the interpretation of such complex and sophisticated networks. This research article focuses on modeling of bio-cellular structures and processes on silicon substrate using transistors in analog domain. MOS transistor analogies for some very commonly found bio-cellular reactions namely receptor–ligand kinetics and Michaelis Menten kinetics have been presented, which are based on...
全文获取路径: Springer Nature  (合作)
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关键词翻译
关键词翻译
  • kinetics 动力学
  • receptor 接受体
  • modeling 制祝型
  • silicon 
  • cellular 细胞状的
  • saturated 饱和
  • corresponding 对应的
  • substrate 基质
  • suggested 建议
  • positively 断然