Anticoagulation therapy for a LVAD patient with acquired warfarin resistance
作者: Daisuke YoshiokaKoichi TodaTakayuki HidakaSoichiro YasudaShunsuke SaitoKeitaro DomaeYoshiki Sawa
作者单位: 1Osaka University Graduate School of Medicine
2Hiroshima University Hospital
刊名: Journal of Artificial Organs, 2017, Vol.20 (3), pp.260-262
来源数据库: Springer Nature Journal
DOI: 10.1007/s10047-017-0947-8
关键词: Left ventricular assist deviceWarfarinAnticoagulation therapy
英文摘要: Anticoagulation therapy with warfarin is essential for postoperative management in patients with left ventricular assist device (LVAD). In this manuscript, we report the case of a patient who developed warfarin resistance after LVAD implantation. Although we administered a novel anticoagulant drug in addition to warfarin and aspirin therapy, the patient developed a major stroke. The patient needed continuous intravenous heparinization until heart transplantation for approximately 2 years. Meticulous management of anticoagulation therapy is essential for a LVAD with warfarin resistance. To our best knowledge, our case is the first case of warfarin resistance in a patient with LVAD.
原始语种摘要: Anticoagulation therapy with warfarin is essential for postoperative management in patients with left ventricular assist device (LVAD). In this manuscript, we report the case of a patient who developed warfarin resistance after LVAD implantation. Although we administered a novel anticoagulant drug in addition to warfarin and aspirin therapy, the patient developed a major stroke. The patient needed continuous intravenous heparinization until heart transplantation for approximately 2 years. Meticulous management of anticoagulation therapy is essential for a LVAD with warfarin resistance. To our best knowledge, our case is the first case of warfarin resistance in a patient with LVAD.
全文获取路径: Springer Nature  (合作)
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来源刊物:
影响因子:1.414 (2012)

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关键词翻译
关键词翻译
  • warfarin 杀鼠灵
  • aspirin 阿司匹林
  • patient 有耐性的
  • essential 本质的
  • heparinization 肝素化
  • postoperative 手术后的
  • anticoagulant 抗凝剂
  • therapy 治疗
  • acquired 获得的
  • developed 开发