Knockdown of microRNA-17-5p ameliorates atherosclerotic lesions in ApoE −/− mice and restores the expression of very low density lipoprotein receptor
作者: Lili TanLiang MengXiaojing ShiBo Yu
作者单位: 1The First Affiliated Hospital of China Medical University
2Central Hospital Affiliated to Shenyang Medical College
3The First Affiliated Hospital of Jinzhou Medical University
刊名: Biotechnology Letters, 2017, Vol.39 (7), pp.967-976
来源数据库: Springer Nature Journal
DOI: 10.1007/s10529-017-2337-y
关键词: AtherosclerosisMicroRNA-17-5pProprotein convertase subtilisin kexin 9Very low density lipoprotein receptor
原始语种摘要: To propose and verify a hypothesis that miR-17-5p knockdown may mitigate atherosclerotic lesions using atherosclerotic ApoE−/− mice as serum microRNA-17-5p (miR-17-5p) is elevated in patients with atherosclerosis.
全文获取路径: Springer Nature  (合作)
影响因子:1.853 (2012)

  • 减轻 假说
  • lipoprotein 脂蛋白
  • density 密度
  • receptor 接受体
  • subtilisin 枯草杆菌蛋白酶
  • expression 表示
  • knockdown 击倒
  • elevated 高的
  • hypothesis 假说
  • mitigate 假说
  • convertase 转化酶