The effect of l -Dopa administration on pursuit ocular movements in suspected Parkinson’s disease
作者: Silvia MarinoPietro LanzafameEdoardo SessaAlessia BramantiPlacido Bramanti
作者单位: 1IRCCS Centro Neurolesi, “Bonino-Pulejo”
刊名: Neurological Sciences, 2010, Vol.31 (3), pp.381-385
来源数据库: Springer Nature Journal
DOI: 10.1007/s10072-009-0180-1
关键词: l -DopaParkinson diseasePursuit ocular movementsVision-based eye-tracking system
英文摘要: Abstract(#br)The objective of this study is to evaluate pursuit ocular movements (POM) by using a vision-based non-intrusive eye tracker, in patients with suspected Parkinson’s disease (PD), before and after l -Dopa administration. We studied ten patients with suspected diagnosis of idiopathic PD. We compared POM values to those of a group of normal controls (NC), and evaluated them before and after l -Dopa administration. Unified Parkinson’s Disease Rating Scale (UPDRS) motor subscores improved significantly ( p = 0.001). At baseline, values of POM were lower in suspected PD patients than in NC ( p = 0.01). One hour after l -Dopa administration, POM values correlated with UPDRS motor subscore ( p = 0.01). We used a recent method, a new vision-based non-intrusive eye tracker, previously...
全文获取路径: Springer Nature  (合作)
影响因子:1.412 (2012)

  • administration 管理
  • pursuit 追踪
  • effect 效应
  • ocular 目镜
  • suspected 涉嫌