Non-neuronal cholinergic activity is potentiated in myasthenia gravis
作者: Bin HanChao ZhangShoufeng LiuYiping XiaHao SunZhongying GongAlain R. SimardQiang LiuJunwei Hao
作者单位: 1Tianjin Medical University General Hospital
2Tianjin HuanHu Hospital
3Laboratory of Physical and Chemical Research, Tianjin Centers for Disease Control and Prevention
4Shandong Provincial Hospital Affiliated to Shandong University
5Tianjin First Center Hospital, Tianjin Medical University
6Université de Moncton
7Barrow Neurological Institute, St. Joseph’s Hospital and Medical Center
刊名: BMC Neurology, 2017, Vol.17 (1)
来源数据库: Springer Nature Journal
DOI: 10.1186/s12883-016-0772-3
关键词: AcetylcholineMyasthenia gravisInflammationCholinergic anti-inflammatory pathway
原始语种摘要: Non–neuronal acetylcholine (ACh) restricts autoimmune responses and attenuates inflammation by cholinergic anti-inflammation pathway. To date, the implication of ACh in myasthenia gravis (MG) remained unexplored. This study aimed to investigate the possible relationship between ACh levels, anti–muscle-specific tyrosine kinase (MuSK) antibody titers, main clinical features and outcomes of MG patients.
全文获取路径: Springer Nature  (合作)
影响因子:2.564 (2012)

  • gravis 重的
  • myasthenia 肌弱
  • cholinergic 胆碱能的
  • inflammation 炎症
  • neuronal 二乙基溴乙酰胺
  • acetylcholine 乙酰胆碱
  • antibody 抗体
  • inflammatory 激怒的
  • autoimmune 自身免疫的
  • pathway 轨道