Cytokeratin7 and cytokeratin19 expression in high grade cervical intraepithelial neoplasm and squamous cell carcinoma and their possible association in cervical carcinogenesis
作者: Hojung LeeHyekyung LeeYong Kyun Cho
作者单位: 1Eulji University
2Gachon University Gil Medical Center
刊名: Diagnostic Pathology, 2017, Vol.12 (1)
来源数据库: Springer Nature Journal
DOI: 10.1186/s13000-017-0609-4
关键词: Cervical cancerSquamocolumnar junctionHPVCK7CK19P16
原始语种摘要: High risk human papillomavirus (HR HPV) infects cells at the squamocolumnar junction (SCJ) of the cervix, causing cancer. Cytokeratin (CK)7 is an SCJ marker, and stains cervical neoplasia. CK19 is a binding partner of CK7 and expressed in cervical cancer. Despite this possible association between CK7/CK19 and cervical cancer, not much is known about the mechanism of CK7/CK19 involvement in HR HPV-mediated cervical carcinogenesis.
全文获取路径: Springer Nature  (合作)
影响因子:1.85 (2012)

  • cervical 颈的
  • carcinogenesis 癌形成
  • squamous 具鳞的
  • association 联合
  • papillomavirus 乳头状瘤病毒
  • cervix 
  • neoplasia 新生物形成
  • neoplasm 赘生物
  • cytokeratin 细胞角蛋白
  • expression 表示