Cell-free hemoglobin mediated oxidative stress is associated with acute kidney injury and renal replacement therapy in severe falciparum malaria: an observational study
作者: Katherine PlewesHugh W.F. KingstonAniruddha GhoseRichard J. MaudeM. Trent HerdmanStije J. LeopoldHaruhiko IshiokaMd. Mahtab Uddin HasanMd. Shafiul HaiderShamsul AlamKim A. PieraPrakaykaew CharunwatthanaKamolrat SilamutTsin W. YeoMd. Abul FaizSue J LeeMavuto MukakaGareth D.H. TurnerNicholas M. AnsteyL. Jackson RobertsNicholas J. WhiteNicholas P.J. DayMd. Amir HossainArjen M. Dondorp
作者单位: 1Faculty of Tropical Medicine, Mahidol University
2University of Oxford
3University of British Columbia Clinical Investigator program
4Menzies School of Health Research and Charles Darwin University
5Chittagong Medical College and Hospital
6Lee Kong Chian School of Medicine, Nanyang Technological University
7Dev Care Foundation
8Faculty of Tropical Medic
刊名: BMC Infectious Diseases, 2017, Vol.17 (1)
来源数据库: Springer Nature Journal
DOI: 10.1186/s12879-017-2373-1
关键词: Acute kidney injuryPathophysiologyFalciparum malariaCell-free hemoglobinOxidative stress
原始语种摘要: Intravascular hemolysis is an intrinsic feature of severe malaria pathophysiology but the pathogenic role of cell-free hemoglobin-mediated oxidative stress in severe malaria associated acute kidney injury (AKI) is unknown.
全文获取路径: Springer Nature  (合作)
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影响因子:3.025 (2012)

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关键词翻译
关键词翻译
  • malaria 疟疾
  • hemoglobin 血红蛋白
  • oxidative 氧化的
  • stress 应力
  • observational 观察的
  • associated 相关的
  • severe 严滥
  • injury 损害
  • kidney 肾脏
  • renal 肾的