Cells in experimental life sciences - challenges and solution to the rapid evolution of knowledge
作者: Sirarat SarntivijaiAlexander D. DiehlYongqun He
作者单位: 1Wellcome Trust Genome Campus
2University at Buffalo, The State University of New York
3University of Michigan Medical School
刊名: BMC Bioinformatics, 2017, Vol.18 (17)
来源数据库: Springer Nature Journal
DOI: 10.1186/s12859-017-1976-2
关键词: Cell cultureCell lineCell ontologyCell line ontologyCell typesHuman cell atlas
原始语种摘要: Cell cultures used in biomedical experiments come in the form of both sample biopsy primary cells, and maintainable immortalised cell lineages. The rise of bioinformatics and high-throughput technologies has led us to the requirement of ontology representation of cell types and cell lines. The Cell Ontology (CL) and Cell Line Ontology (CLO) have long been established as reference ontologies in the OBO framework. We have compiled a series of the challenges and the proposals of solutions in this CELLS (Cells in ExperimentaL Life Sciences) thematic series that cover the grounds of standing issues and the directions, which were discussed in the First International Workshop on CELLS at the the International Conference on Biomedical Ontology (ICBO). This workshop focused on the extension of the...
全文获取路径: Springer Nature  (合作)
影响因子:3.024 (2012)

  • knowledge 知识
  • maintainable 修]可维护[修
  • ontology 本体论
  • International 国际的国际性组织
  • biomedical 生物医学
  • driven 从动的
  • infrastructure 下层构造
  • bioinformatics 生物信息学
  • leverage 杠杆率
  • cover 覆盖