Calycosin inhibits the in vitro and in vivo growth of breast cancer cells through WDR7-7-GPR30 Signaling
作者: Jing TianYong WangXing ZhangQianyao RenRong LiYue HuangHuiling LuJian Chen
作者单位: 1Guilin Medical University
2First Affiliated Hospital of Guilin Medical University
刊名: Journal of Experimental & Clinical Cancer Research, 2017, Vol.36 (1)
来源数据库: Springer Nature Journal
DOI: 10.1186/s13046-017-0625-y
关键词: CalycosinLong non-coding RNAWDR7-7GPR30Breast cancer
英文摘要: Clinically, breast cancer is generally classified into estrogen receptor-positive (ER+) or estrogen receptor-negative (ER−) subtypes. The phytoestrogen calycosin has been shown to inhibit the proliferation of ER+ cells, which may be mediated by a feedback loop that involves miR-375, RAS dexamethasone-induced 1 (RASD1), and ERα. However, how calycosin acts on ER− breast cancer cells remains unclear.
原始语种摘要: Clinically, breast cancer is generally classified into estrogen receptor-positive (ER+) or estrogen receptor-negative (ER−) subtypes. The phytoestrogen calycosin has been shown to inhibit the proliferation of ER+ cells, which may be mediated by a feedback loop that involves miR-375, RAS dexamethasone-induced 1 (RASD1), and ERα. However, how calycosin acts on ER− breast cancer cells remains unclear.
全文获取路径: Springer Nature  (合作)
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关键词翻译
关键词翻译
  • breast 胸部
  • estrogen 雌激素
  • GPR General Purpose Register
  • cells 麻风细胞
  • cancer 癌症
  • receptor 接受体
  • coding 编码
  • remains 残渣
  • unclear 不清楚的
  • RAS Random Access Storage