Rapid and multimodal in vivo bioimaging of cancer cells through in situ biosynthesis of Zn&Fe nanoclusters
作者: Tianyu DuChunqiu ZhaoFawad ur RehmanLanmei LaiXiaoqi LiYi SunShouhua LuoHui JiangMatthias SelkeXuemei Wang
作者单位: 1Southeast University
2Nanjing Foreign Language School
3California State University
刊名: Nano Research, 2017, Vol.10 (8), pp.2626-2632
来源数据库: Springer Nature Journal
DOI: 10.1007/s12274-017-1465-y
关键词: Multimodal imagingBiosynthesizedZn&Fe oxide nanoclustersCancer diagnosis
英文摘要: Early diagnosis remains highly important for efficient cancer treatment, and hence, there is significant interest in the development of effective imaging strategies. This work reports a new multimodal bioimaging method for accurate and rapid diagnosis of cancer cells by introducing aqueous Fe2+ and Zn2+ ions into cancer cells (i.e., HeLa, U87, and HepG2 cancer cells). We found that the biocompatible metal ions Fe2+ and Zn2+ forced the cancer cells to spontaneously synthesize fluorescent ZnO nanoclusters and magnetic Fe3O4 nanoclusters. These clusters could then be used for multimodal cancer imaging by combining fluorescence imaging with magnetic resonance imaging and computed tomography imaging. Meanwhile, for normal cells...
原始语种摘要: Early diagnosis remains highly important for efficient cancer treatment, and hence, there is significant interest in the development of effective imaging strategies. This work reports a new multimodal bioimaging method for accurate and rapid diagnosis of cancer cells by introducing aqueous Fe2+ and Zn2+ ions into cancer cells (i.e., HeLa, U87, and HepG2 cancer cells). We found that the biocompatible metal ions Fe2+ and Zn2+ forced the cancer cells to spontaneously synthesize fluorescent ZnO nanoclusters and magnetic Fe3O4 nanoclusters. These clusters could then be used for multimodal cancer imaging by combining fluorescence imaging with magnetic resonance imaging and computed tomography imaging. Meanwhile, for normal cells...
全文获取路径: Springer Nature  (合作)
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影响因子:7.392 (2012)

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关键词翻译
关键词翻译
  • 荧光 生物相容的
  • multimodal 多峰
  • imaging 图像形成
  • Rapid 拉皮德牌照相机
  • cells 麻风细胞
  • efficient 有用的
  • accurate 精确的
  • tomography 断层x 线摄影
  • through 经过
  • biocompatible 生物相容的
  • fluorescence 生物相容的