The effect of a novel probiotic on metabolic biomarkers in adults with prediabetes and recently diagnosed type 2 diabetes mellitus: study protocol for a randomized controlled trial
作者: Talia PalaciosLuis VitettaSamantha CoulsonClaire D. MadiganGareth S. DenyerIan D. Caterson
作者单位: 1The Boden Institute of Obesity, Nutrition, Exercise and Eating Disorders, University of Sydney
2University of Sydney, Sydney Medical School
3Medlab Clinical
4School of Life and Environmental Sciences, University of Sydney
刊名: Trials, 2017, Vol.18 (1)
来源数据库: Springer Nature Journal
DOI: 10.1186/s13063-016-1762-x
关键词: Gut microbiotaPrediabetesProbioticsType 2 diabetes mellitus
英文摘要: Shifts in the gastrointestinal microbiome have been shown to contribute to the progression of metabolic diseases including prediabetes and type 2 diabetes mellitus. Research suggests that in-vivo modulation of the gut microbiome by specific probiotic microorganisms may improve insulin sensitivity and blood sugar management, preventing or delaying the development of type 2 diabetes mellitus. However, further research is needed to understand the effect of probiotics as a therapy for the treatment of metabolic diseases. An evidence-based multi-species probiotic was developed to encourage a shift in the gastrointestinal bacterial cohort from a disease-prone to a balanced state with the aim of improving metabolic markers associated with type 2 diabetes mellitus.
原始语种摘要: Shifts in the gastrointestinal microbiome have been shown to contribute to the progression of metabolic diseases including prediabetes and type 2 diabetes mellitus. Research suggests that in-vivo modulation of the gut microbiome by specific probiotic microorganisms may improve insulin sensitivity and blood sugar management, preventing or delaying the development of type 2 diabetes mellitus. However, further research is needed to understand the effect of probiotics as a therapy for the treatment of metabolic diseases. An evidence-based multi-species probiotic was developed to encourage a shift in the gastrointestinal bacterial cohort from a disease-prone to a balanced state with the aim of improving metabolic markers associated with type 2 diabetes mellitus.
全文获取路径: Springer Nature  (合作)
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来源刊物:
影响因子:2.206 (2012)

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关键词翻译
关键词翻译
  • prediabetes 前驱糖尿病
  • metabolic 新陈代谢的
  • probiotic 前生命期的
  • microbiota 微生物区系
  • trial 试验
  • insulin 胰岛素
  • delaying 延迟
  • controlled 受控
  • effect 效应
  • novel 长篇小说