Response to neoadjuvant chemotherapy for breast cancer judged by PERCIST – multicenter study in Japan
作者: Kazuhiro KitajimaKoya NakataniKazushige YamaguchiMasatoyo NakajoAtsushi TaniMana IshibashiKeiko HosoyaTakahiro MoritaTakayuki KinoshitaHayato KaidaYasuo Miyoshi
作者单位: 1Department of Radiology, Division of Nuclear Medicine and PET Center, Hyogo College of Medicine
2Department of Diagnostic Radiology, Kurashiki Central Hospital
3Department of General Surgery, Kurashiki Central Hospital
4Department of Radiology, Graduate School of Medical and Dental Sciences, Kagoshima University
5Department of Pathophysiological and Therapeutic Sciences, Division of Radiology, Tottori University
6Division of Breast Cancer and Endocrine Surgery, Faculty of Medicine, Tottori University
7Department of Diagnostic Radiology, National Cancer Center Hospital
8Department of Breast Surgery, National Cancer Center Hospital
9Department of Radiology, Kinki University Faculty of Medicine
10Department of Breast and Endocrine Surgery, Hyogo College of Medicine
刊名: European Journal of Nuclear Medicine and Molecular Imaging, 2018, Vol.45 (10), pp.1661-1671
来源数据库: Springer Nature Journal
DOI: 10.1007/s00259-018-4008-1
关键词: Breast cancerFDG-PET/CTPERCISTTreatment responsePrognosis
英文摘要: Abstract(#br) Purpose(#br)The purpose of this study was to evaluate therapeutic response to neoadjuvant chemotherapy (NAC) and predict breast cancer recurrence using Positron Emission Tomography Response Criteria in Solid Tumors (PERCIST).(#br) Materials and methods(#br)Fifty-nine breast cancer patients underwent fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT) before and after NAC prior to planned surgical resection. Pathological complete response (pCR) of the primary tumor was evaluated using PERCIST, while effects of clinicopathological factors on progression-free survival (PFS) were examined using log-rank and Cox methods.(#br) Results(#br)Fifty-six patients and 54 primary tumors were evaluated. Complete metabolic response (CMR), partial metabolic...
全文获取路径: Springer Nature  (合作)