Overexpression of dishevelled 2 is involved in tumor metastasis and is associated with poor prognosis in hepatocellular carcinoma
作者: C. ZhangC. LiX. ChenY. ZhouB. YinR. NiY. ZhangJ. Liu
作者单位: 1Nantong University
2Affiliated Cancer Hospital of Nantong University
3Affiliated Hospital of Nantong University
刊名: Clinical and Translational Oncology, 2017, Vol.19 (12), pp.1507-1517
来源数据库: Springer Nature Journal
DOI: 10.1007/s12094-017-1697-z
关键词: Dishevelled 2Hepatocellular carcinomaPrognosisMetastasis
英文摘要: Although hepatocellular carcinoma (HCC) is one of the most common malignant tumors, its molecular mechanism is still unknown. Dishevelled 2 (Dvl2) is one of the downstream targets of non-canonical Wnt signaling, which has been demonstrated to be of great importance in the progression of cancers. Nevertheless, the expression mechanisms and physiological significance of Dvl2 in HCC remain unclear.
原始语种摘要: Although hepatocellular carcinoma (HCC) is one of the most common malignant tumors, its molecular mechanism is still unknown. Dishevelled 2 (Dvl2) is one of the downstream targets of non-canonical Wnt signaling, which has been demonstrated to be of great importance in the progression of cancers. Nevertheless, the expression mechanisms and physiological significance of Dvl2 in HCC remain unclear.
全文获取路径: Springer Nature  (合作)
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影响因子:1.276 (2012)

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关键词翻译
关键词翻译
  • hepatocellular 肝细胞性的
  • carcinoma 癌症
  • metastasis 同质蜕变
  • prognosis 预报
  • involved 涉及
  • tumor 肿胀
  • downstream 顺聊
  • associated 相关的
  • unclear 不清楚的
  • importance 重要性